Biochemistry 118

Sophomore Seminar

Genomics & Medicine

Doug Brutlag

 

In this seminar we will discuss the kind of knowledge we hope to gain from sequencing human and bacterial genomes and the implications of such knowledge for medicine and biomedical research. We will discuss novel diagnoses and treatment of diseases, including stem cells, gene therapy and rational drug design. We will also discuss the ethical implications of genetic information.

The course will be of interest to students who plan to major in biology or human biology, especially premedical students and biology majors who use molecular biology methods. It will also be useful to those interested in health care policy, intellectual-property rights and ethical issues.

Homework will include using genome and disease databases to determine the function of genes involved in disease. There are no prerequisites for this course.

Topics for Discussion

  1. Genomics
  2. Bioinformatics
  3. Stem Cell Therapies
  4. Gene Therapy
  5. Patent Policy
  6. Drug Development and the Pharmaceutical Industry
  7. Ethical Issues and Genetic Discrimination
  8. Novel Molecular Diagnostics
  9. DNA Structure
  10. Protein Structure
  11. Infectious Disease
  12. Web Resources for the course

Projects Previously Submitted for the Course

1999

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2002

2002 Stanford Overseas Program

2003

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2005

2007

2008