Biochemistry 118

Sophomore Seminar


Genomics & Medicine

Doug Brutlag

Gene Expression and Cancer Diagnostics

Lecture Rerources on Gene Expression

Gene Expression Slides

Programs for finding Transcription Factor Binding Sites





Melina II


Papers on diagnosing Breast Cancer using Gene Expression MicroArrays

Sorlie et al PNAS 2001 PNAS September 11, 2001 vol. 98 page 10871

Lonning et al. Endocrine-Related Cancer (2001) 8 259-263

The ENCODE Project

ENCODE: The human encyclopedia

Recent Literature on Gene Expression Profiles and Disease

Web Resources


Arrayit Corporation

Biocarta Cell Signaling Pathways


miRNA Target Database MicroCom

PathWork Diagnostics








Lectures only available to Stanford Students

Henry Stewart Talks

Accessing and Using ENCODE Data (44 mins)  Prof. Peggy Farnham  –  University of California in Davis, USA

The basal transcription machinery for RNA polymerase II (42 mins)  Prof. H. T. Marc Timmers  –  University of Utrecht, the Netherlands

Genome-wide organization of chromatin and the transcription machinery (48 mins)  Prof. Frank Pugh  –  Pennsylvania State University

The Myc transcription factor network (47 mins)  Prof. Robert N. Eisenman  –  Fred Hutchinson Cancer Research Center, USA

Role of polycomb proteins in gene transcription, stem cell and human diseases Prof. Luciano Di Croce  –  Center for Genomic Regulation

Heterochromatin, epigenetics and gene expression (51 mins)  Prof. Joel C. Eissenberg  –  Saint Louis University, USA

Histone dynamics, heritability and variants (38 mins)  Dr. Genevieve Almouzni  –  Curie Institute/CNRS, France

Enhancer malfunction in cancer (41 mins)  Dr. Ali Shilatifard  –  Stowers Institute, USA

Genetic variation in gene regulation - Prof. Jonathan Pritchard

Medical Grand Rounds

Roger Kornberg, Professor of Structural Biology, Nobel Laureate - Transcription in Development and Disease

Mark Pegram, Prof. of Medicine – Therapeutic strategies targeting ERBB2

Hanlee Ji,  Stanford Oncology – The Genetics of Personalized Cancer Medicine

Ross Levine, Professor of Medicine, Weill Cornell - –Genetics and therapy of Acute Myeloid Leukemia

Steve Coutre, Chief Resident, Stanford Department of Medicine–Chronic Lymphatic Leukemia: Do we have a cure?

Marc Lipman, University of Miami - Will we ever cure Breast Cancer?