Biochemistry 118

Genomics & Medicine

Doug Brutlag

Genomics

Slides for Lectures on Genomics

Genomics Slides

Genome Database Slides

Gene Expression Slides

miRNA Regulatory Network Slides

Genomic Web Resources

Human Genome Project

Human Genome Primer

NCBI Human Genome Resources http://www.ncbi.nlm.nih.gov/genome/guide/human/

EBI ENSEMBL Human Genome Server http://www.ensembl.org/Homo_sapiens/

UCSC Genome Browser http://genome.ucsc.edu/

Genetic Information Nondiscrimination Act HR 493 2008

Summary

Full Text

Sequencing Strategies

Mathematical Model for Genome Mapping, Lander & Waterman 1987

Whole Shotgun Sequencing of the Human Genome Weber and Myers 1997

Against a Whole Shotgun Sequencing of the Human Genome, 1997

Human Genome as of 2001

Public Human Genome Project Publication In Nature 15 February 2001

Initial Sequencing and Analysis of the Human Genome Paper (Pulbic Effort)

Commercial Human Genome Sequence Published in Science 16 February 2001

The Sequence of the Human Genome (Celera)

Final Human Genome

Finishing the Euchromatic Sequence of the Human Genome 2004

The Diploid Genome Sequence of an Individual Human 2007

Next Generation Sequencing Technologies

Illumina - Solexa

Illumina Technology

454 Life Sciences

454 Life Sciences Technology

Applied Biosystems Inc. (ABI) SOLID Sequencing

ABI SOLID Sequencing Technology

Pacific BioSciences

Pacific BioSciences Technology

Helicos

Helicos Technology

Complete Genomics

Complete Genomics Technology

Societal and Ethical Issues

Advantages & Issues of Genome Diagnoses

Nature versus Nuture Our genes and cancer

What is immoral about eugenics?

Genomics and Society

Genomic Privacy July 12, 2002

Discrimination is Good

DNA Sequencing FAST

Genome Analysis Shows Humans Survive on Low Numbers of Genes (Nicholas Wade 2001)

Genome's Riddle: Few Genes, Much Complexity (Nicholas Wade 2001)

Grad Student Becomes Gene Effort's Unlikely Hero (Nicholas Wade 2001)

Genome shows Evolution Has an Eye for Hyperbole (Natalie Angier 2001)

Double Helix With a Twist (Andrew Pollack 2001)

Papers on diagnosing Breast Cancer using Gene Expression MicroArrays

Sorlie et al PNAS 2001 PNAS September 11, 2001 vol. 98 page 10871

Lonning et al. Endocrine-Related Cancer (2001) 8 259&endash;263

Estonian Genome Project Documents

Estonian Genome Project

Estonian Genome Project Slides

Estonian HumanGenesResearchAct.

Estonian Gene Donor Consent Form